Ingredient Profile · Botanical
Stinging Nettle Root
Competes with testosterone for SHBG binding sites.
Mechanism
Stinging Nettle Root contains lignans studied for competing with testosterone for binding sites on SHBG (sex hormone-binding globulin), helping keep more testosterone free and biologically active — complementary to Tongkat Ali's separate SHBG-related mechanism.
What the evidence shows
The SHBG-binding mechanism is documented in laboratory research; human trial data isolating Nettle Root's specific effect on free testosterone is more limited than for some other formula ingredients.
Safety notes
Generally well tolerated. Can interact with blood pressure medication and diuretics — consult a doctor before use if you take either.